Ischemic Postconditioning and Milrinone

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Ischemic postconditioning: a clinical perspective

Acute myocardial infarction is a major cause of death and heart failure in western society [1]. Introduction of reperfusion therapy in terms of thrombolysis and primary percutaneous coronary intervention (PPCI) has lead to a significant decreases in morbidity and mortality [2]. Today, PPCI is the recommended therapy for patients with ST-segment elevation myocardial infarction (STEMI). However, ...

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Survival kinases in ischemic preconditioning and postconditioning.

Despite nearly twenty years of research into the field of ischemic preconditioning, the actual mechanism of protection remains unclear. However, much progress has been made in elucidating the signal transduction pathways that convey the extracellular signal initiated by the preconditioning stimulus to the intracellular targets of cardioprotection, with many of these pathways involving the activ...

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Ischemic Postconditioning Attenuates Bilateral Renal Ischemia-Induced Cognitive Impairments

Background and aim: Acute kidney injury (AKI) is a frequent complication of kidney failure with high mortality which leads to brain dysfunction. The aim of this study was to investigate the possible protective effect of ischemic postconditioning (IPo) against brain dysfunction induced by bilateral renal ischemia (BRI). Materials and methods: Male Wistar rats underwent BRI, sham or IPo surgery ...

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Remote ischemic postconditioning during percutaneous coronary interventions: remote ischemic postconditioning-percutaneous coronary intervention randomized trial.

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ژورنال

عنوان ژورنال: Journal of Cardiothoracic and Vascular Anesthesia

سال: 2018

ISSN: 1053-0770

DOI: 10.1053/j.jvca.2018.01.047